Category Archives: Uncategorized

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Network and modelling-based analysis revealed a regulatory core underlying E2F1-mediated epithelial-mesenchymal transition in aggressive cancers

We constructed a map of the regulatory network around the E2F family, and using gene expression profiles, identify tumour type-specific regulatory cores and receptor expression signatures associated with epithelial-mesenchymal transition.

https://www.ncbi.nlm.nih.gov/pubmed/28775339

 


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A web platform for the network analysis of highthroughput data in melanoma

We have developed the Virtual Melanoma Cell, an online tool developed to facilitate the mining and interpretation of high-throughput data on melanoma by biomedical researches. The platform is based on a comprehensive, manually generated and expert-validated regulatory map composed of signaling pathways important in malignant melanoma. The Virtual Melanoma Cell is a tool designed to accept, visualize and analyze user-generated datasets. It is available at: https://www.vcells.net/melanoma

https://www.ncbi.nlm.nih.gov/pubmed/29410200